Algorithm 1 of 7
Adult Cardiac Arrest
Shockable & non-shockable pathways — CPR & defibrillation
Unresponsive · No Breathing / Only Gasping
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✓ YES — Definite Pulse
- Give 1 breath every 6 seconds
- Recheck pulse every 2 minutes
↓
✗ NO — No Pulse
⚡
Activate Team · Begin CPR — 30 compressions : 2 breaths
- Continuous compressions until BVM available
- O₂ at 15L/min when available
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High-Quality CPR
- Rate ≥ 100/min · Depth ≥ 5cm · Full recoil after each compression
- Interruptions < 10 sec · If intubated: 1 breath every 6 sec
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⚡ VF / Pulseless VT
⚡
SHOCK — Biphasic 200J · Monophasic 360J
↓
- IV/IO access · Bloods: VBG & RBS
- Attach leads; monitor lead II
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⚡ Still Shockable
⚡
SHOCK — Biphasic 200J · Monophasic 360J
↓
Adrenaline 1mg IV/IO + 20mL NS flush
Repeat after 2 CPR cycles · Identify & treat reversible causes
Repeat after 2 CPR cycles · Identify & treat reversible causes
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⚡ Still Shockable
⚡
SHOCK — Biphasic 200J · Monophasic 360J
↓
1st dose: Amiodarone 300mg IV/IO + 20mL NS flush
2nd dose (after 2 cycles): 150mg IV/IO + 20mL NS flush
Consider advanced airway & capnography
2nd dose (after 2 cycles): 150mg IV/IO + 20mL NS flush
Consider advanced airway & capnography
↻ Continue — rhythm check every 2-min CPR cycle
✗ No — PEA/Asystole loop
↻ Adrenaline every 2 CPR cycles · Check for ROSC
✗ No — PEA/Asystole loop
↻ Continue PEA/Asystole — Adrenaline every 2 cycles
✗ Asystole / PEA
- IV/IO access · Bloods: VBG & RBS
- Attach leads; monitor lead II
↓
Adrenaline 1mg IV/IO + 20mL NS flush
Repeat after 2 CPR cycles · Consider advanced airway & capnography
Repeat after 2 CPR cycles · Consider advanced airway & capnography
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⚡ Now Shockable
↻ Follow VF/Pulseless VT path above
✗ Still Non-Shockable
↻ Adrenaline every 2 CPR cycles · Check for ROSC
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🔍 Reversible Causes — H's & T's
The H'sHypoglycaemia · Hypovolemia · Hypoxia · Hydrogen ion (acidosis) · Hypo/hyperkalaemia · Hypothermia
The T'sTension Pneumothorax · Tamponade (cardiac) · Toxins · Thrombosis (pulmonary) · Thrombosis (coronary)
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MedPearls
Algorithm 2 of 7
Adult Bradycardia
HR < 50/min with pulse — identify instability
Adult Bradycardia — HR < 50/min with Pulse
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- Airway: Open, maintain, protect as necessary
- Breathing: O₂ if SpO₂ < 94%; assist as needed
- Circulation: Cardiac monitor · BP · SpO₂ · ToC · RBS · IV access · FBC, UEC, VBG · 12-lead ECG — don't delay therapy
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⚠ UNSTABLE
Notify cardiologist immediately while initiating treatment below.
↓
IV Atropine — First Line
First dose: 0.5mg bolus
Repeat every 3–5 min · Max: 3mg
Exclude before use: head injury · hypoxia · hypothermia · heart block · hyperkalaemia · heart transplant
↓
✓ Atropine Effective
Continuous ECG monitoring · repeat vitals · assess for underlying cause.
✗ Ineffective — Second Line
Transcutaneous Pacing
See pacing protocol
First-line if atropine fails
Dopamine Infusion
2–10 µg/kg/min IV
Adrenaline Infusion
2–10 µg/min IV
Glucagon
If β-blocker or CCB overdose
↓
📞
Consult a Cardiologist — urgent
✓ STABLE
Reversible Causes — H's & T'sHypoglycaemia · Hypovolemia · Hypoxia · Hydrogen ion (acidosis) · Hypo/hyperkalaemia · Hypothermia · Tension Pneumothorax · Tamponade · Toxins · Thrombosis
MedPearls
Algorithm 3 of 7
Adult Tachycardia
HR > 150/min with pulse — stability & QRS width
Adult Tachycardia — HR > 150/min with Pulse
↓
- Airway: Open, maintain, protect as necessary
- Breathing: O₂ if SpO₂ < 94%; assist as needed
- Circulation: Cardiac monitor · BP · SpO₂ · IV access · FBC, UEC, VBG · 12-lead ECG — don't delay therapy
↓
⚠ UNSTABLE — Immediate Action
🔴
Synchronised Cardioversion
- Start 100J — escalate as needed
- Consider procedural sedation · Consult Cardiologist
↓
- Defibrillation (asynchronous)
- Magnesium 2g IV over 10 mins
- Overdrive pacing
✓ STABLE — Assess QRS Width
📉 NARROW — SVT (QRS < 0.12s)
NOT if varying R-R intervals / Atrial fibrillation
- Valsalva (abdominal pressure / breath holding)
- Facial application of ice water
- Carotid sinus massage — C/I if bruits, CVS disease, elderly
↓
Adenosine
6mg rapid IV push + 20mL NS flush
Then 12mg IV after 1–2 mins if needed
NOT if varying R-R intervals / Atrial fibrillation
↓
β-blockers · Calcium channel blockers · Digoxin
Consult a Cardiologist
Consult a Cardiologist
📈 WIDE — VT (QRS ≥ 0.12s)
Adenosine
6mg rapid IV push + 20mL NS flush
Then 12mg after 1–2 mins
NOT if varying R-R / Polymorphic VT
Amiodarone
150mg IV over 10 mins
then 1mg/min × 6 hours
↓
🔴
Synchronised Cardioversion
- Start 100J — escalate as needed
- Consider procedural sedation · Consult Cardiologist
MedPearls
Algorithm 4 of 7
Post-Cardiac Arrest Care
ROSC — ventilation, hypotension, temperature management
Return of Spontaneous Circulation (ROSC)
↓
- Monitor ABCs · Prepared for CPR & defibrillation
- Vital signs: BP, PR, RR, SpO₂, ToC, RBS
- 12-lead ECG immediately
- If stable → transfer to ICU attached to defibrillator
↓
- Avoid excessive ventilation — start 10–12 breaths/min
- Titrate FiO₂ to maintain SpO₂ ≥ 94%
- Target PETCO₂ 35–45 mmHg
- Consider advanced airway & waveform capnography
↓
Fluid Bolus1–2L Normal Saline or Ringers Lactate IV/IO
If no response — VasopressorAdrenaline: 0.1–0.5 µg/kg/min IV (7–35 µg/min in 70kg adult)
Norepinephrine: 0.1–0.5 µg/kg/min IV (7–35 µg/min in 70kg adult)
If no response — VasopressorAdrenaline: 0.1–0.5 µg/kg/min IV (7–35 µg/min in 70kg adult)
Norepinephrine: 0.1–0.5 µg/kg/min IV (7–35 µg/min in 70kg adult)
↓
Mandatory cardiology consultation if STEMI or ACS suspected.
↓
Keep temp < 36°C for 36 hours
Ice-cold fluids · Ice packs · Intravascular or surface temperature-management
Ice-cold fluids · Ice packs · Intravascular or surface temperature-management
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✓ Follows Commands
Continuous ECG · serial vitals · neurological assessment · CCU/ICU care.
✗ Cannot Follow Commands
Maintain temperature management. Neurological prognostication after 72h of normothermia.
↓
🟢
Transfer to ICU/CCU — connected to defibrillator
MedPearls
Algorithm 5 of 7
ACS Algorithm
12-lead ECG within 10 min of ER arrival
Chest discomfort suggestive of ischemiaEar, jaw, neck, shoulder, arm, back, epigastric pain; dyspnoea; nausea/vomiting; diaphoresis; fatigue
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⏱
12-lead ECG within 10 minutes of ER arrival
- V4R if ST↑ V1 + ST↓ V2 → Right-sided STEMI
- V7–V9 if ST↓ ≥1mm + upright T in ≥2 anterior leads → Posterior STEMI
- ST↑ aVR ≥1mm + widespread ST↓ → Interventional Cardiology immediately (L main/LAD)
- Sinus tach + T inversion III,V1,V3 or S1Q3T3 → Pulmonary Embolism Algorithm
↓
- Prepared for CPR & defibrillation
- Vital signs: BP, PR, RR, SpO₂, ToC, RBS
- O₂ if SpO₂ < 90% or dyspnoeic — maintain SpO₂ ≥ 90%
- IV access: left forearm or antecubital vein
- Bloods: UEC, Coagulation screen, hsTroponin T (if ≥4h from symptom onset)
- Brief targeted history & exam — document symptom onset time
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Aspirin
300mg to chew
If not given by EMS · not allergic · no active UGI/retinal bleed · not haemophiliac · no severe untreated BP
Nitroglycerin SL Spray
0.4mg SL every 5 min — MAX 3 doses
DO NOT give if: SBP <90mmHg or 30mmHg below baseline · HR >100 or <50 bpm · RV infarction · Sildenafil/vardenafil ×24h or tadalafil ×48h
Fentanyl
50µg IV if pain NOT relieved by 3 nitro doses
Repeat once after 5 min if still in pain
Persistent pain → consult Cardiologist · consider IVI nitroglycerin
↓
Rule out: pulmonary embolus · cardiac tamponade · aortic dissection · tension pneumothorax
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🔴 STEMI
🟡 High-Risk UA/NSTEMI
🔵 Intermediate/Low Risk UA
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Sgarbossa Criteria for LBBB — either criterion sufficient
- 1. Concordant ST elevation ≥ 1mm in at least 1 lead
- 2. Concordant ST depression ≥ 1mm in V1–3
MedPearls
Algorithm 6 of 7
STEMI Algorithm
PCI within 90 min · Fibrinolysis within 30 min if PCI unavailable
ST Elevation or LBBB meeting Sgarbossa criteria — STEMI
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| Criteria | Pts | Score | 30-Day Mortality (%) |
|---|---|---|---|
| Age ≥ 75 | 3 | 0 | 0.8 |
| Age 65–74 | 2 | 1 | 1.6 |
| DM / HTN / Angina | 1 | 2 | 2.2 |
| SBP < 100 mmHg | 3 | 3 | 4.4 |
| HR > 100 bpm | 2 | 4 | 7.3 |
| Killip class 2–4 | 2 | 5 | 12 |
| Weight < 67 kg | 1 | 6 | 16 |
| — | — | 7 | 23 |
| Anterior STE or LBBB | 1 | 8 | 27 |
| Time to Rx > 4 hrs | 1 | >8 | 36 |
Score 0–14 · Entry: CP >30 min, ST↑, onset <6h, fibrinolytic-eligible
↓
✗ > 12 hours
📞
Consult an Interventional Cardiologist
✓ ≤ 12 hours — Reperfusion
⭐ PRIMARY PCI — Preferred
⏱
Cathlab within 90 minutes of ER arrival
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Pre-PCI Medications
Clopidogrel 600mg OR Prasugrel 60mg OR Ticagrelor 180mg
Atorvastatin 80mg
Obtain informed consent
💊 FIBRINOLYSIS
Pre-Fibrinolysis Drugs
1. Clopidogrel 600mg
2. Enoxaparin:
<75y: 30mg IV bolus then 1mg/kg SC (max 100mg ×2)
≥75y: no bolus · 0.75mg/kg SC (max 75mg ×2)
CrCl <30: 1mg/kg SC (any age)
3. Atorvastatin 80mg
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Absolute Contraindications
- Any prior intracranial haemorrhage
- Structural cerebral vascular lesion (e.g. AVM)
- Malignant intracranial neoplasm
- Ischaemic stroke within 3 months (EXCEPT acute within 3h)
- Suspected aortic dissection
- Active bleeding or bleeding diathesis (excluding menses)
- Significant closed head/facial trauma within 3 months
- Chronic severe poorly controlled hypertension
- SBP >180 or DBP >110 mmHg on presentation
- Prior ischaemic stroke >3 months / dementia / intracranial pathology
- CPR >10 min or major surgery <3 weeks
- Internal bleeding within 2–4 weeks
- Non-compressible vascular punctures
- Streptokinase: prior exposure >5 days or prior allergic reaction
- Pregnancy · Active peptic ulcer
- Anticoagulants: higher INR = higher bleed risk
↓
Obtain informed consent · Connect to defibrillator (ECG, SpO₂, BP) · Repeat baseline vitals
↓
TENECTEPLASE
<60kg → 30mg (6mL)
60–69kg → 35mg (7mL)
70–79kg → 40mg (8mL)
80–89kg → 45mg (9mL)
≥90kg → 50mg (10mL)
IV bolus over 5 sec · Reconstitute: 50mg vial in 10mL sterile water (5mg/mL)
STREPTOKINASE
1.5 million U in 50mL D5W IV over 60 min
Set up 2nd IV line · Run NS/RL TKVO in other line · Allergic reactions may force early termination
↓
Continue monitoring 30 min post-infusion · Transfer to CCU/ICU connected to defibrillator
MedPearls
Algorithm 7 of 7
UA / NSTEMI Algorithm
Risk stratification — hsTroponin T and TIMI score
High-Risk UA/NSTEMI or Intermediate/Low Risk UAST depression >0.5mm or T-inversion ≥2mm — OR — Normal/non-diagnostic changes
↓
Risk Factors — each = 1 point (0–7 total)
- Age > 65 years
- ≥ 3 CAD risk factors (family Hx, HTN, hypercholesterolaemia, DM, current tobacco)
- Known coronary stenosis ≥ 50%
- ST-segment deviation
- ≥ 2 anginal events in previous 24 hours
- Aspirin use in previous 7 days
- Elevated serum cardiac markers (hsTrop T)
| TIMI Score | 30-Day Risk: Death/MI/Revasc (%) |
|---|---|
| 0 | 2.1 |
| 1 | 5.0 |
| 2 | 10.1 |
| 3 | 19.5 |
| 4 | 22.1 |
| 5 | 39.2 |
| 6 | 45.0 |
| 7 | 100.0 |
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🔴 HIGH RISK
📞
Consult a Cardiologist / Physician — urgent
↓
Serial ECGs to detect dynamic changes or evolution to STEMI.
↓
→ STEMI
✗ No STEMI — NSTEMI Management
Antiplatelet therapy · anticoagulation · early invasive vs conservative strategy per cardiology guidance.
✗ hsTroponin T < 14ng/L
⚠ Elevated Risk
📞
Consult Cardiologist / Physician
↓
Serial ECG monitoring for dynamic changes.
✓ Low Risk — Assess for Discharge
Discharge Criteria — must meet ALL
- Two ECGs: Normal · No ST depression · No dynamic changes
- hsTroponin T < 14ng/L at ≥ 4h from symptom onset OR 3h from ER admission
- If Troponin done <4h from symptom onset → repeat at 3h from ER admission
↓
Arrange outpatient cardiology review as clinically indicated. Patient education and safety netting.
MedPearls